Projects
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VEXAS Syndrome: A newly discovered disease and a call to action
I am an MD/PhD candidate within the laboratory of David B. Beck at the NYU Grossman School of Medicine. My thesis work revolves around elucidating the mechanism of disease in patients with VEXAS Syndrome and characterizing the role of the master regulator of the Ubiquitin-Proteasome System (UPS), UBA1, in physiological and disease states. VEXAS was…
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Envirobe: Engineering microbial machines to tackle mankind’s waste
In 2019, I co-founded Envirobe, a biotech startup angled at solving the growing plastic crisis. By 2025 20% of global oil production will be required to sustain the plastics production industry; furthermore, as most plastic is used once before being discarded, over 95% of its economic and energy value, equaling $120 billion annually, is lost…
Recent Publications
- Beck DB, Bodian DL, Shah V, Mirshahi UL, Kim J, Ding Y, Magaziner SJ, Strande NT, Cantor A, Haley JS, Cook A, Hill W, Schwartz AL, Grayson PC, Ferrada MA, Kastner DL, Carey DJ, Stewart DR. Estimated Prevalence and Clinical Manifestations of UBA1 Variants Associated With VEXAS Syndrome in a Clinical Population. JAMA. 2023
- Stiburkova B, Pavelcova K, Belickova M, Magaziner SJ, Collins JC, Werner A, Beck DB, Balajkova V, Salek C, Vostry M, Mann H, Vencovsky J. Novel somatic UBA1 variant in a patient with VEXAS syndrome. Arthritis Rheumatol. 2023
- Magaziner SJ, Salmond GPC. A novel T4- and λ-based receptor binding protein family for bacteriophage therapy host range engineering. Front Microbiol. 2022
- Gago J, Filardo TD, Conderino S, Magaziner SJ, Dubrovskaya Y, Inglima K, Iturrate E, Pironti A, Schluter J, Cadwell K, Hochman S, Li H, Torres VJ, Thorpe LE, Shopsin B. Pathogen Species Is Associated With Mortality in Nosocomial Bloodstream Infection in Patients With COVID-19. Open Forum Infect Dis. 2022